Basic Description:

Erlotinib - Tarceva "Erlotinib hydrochloride (trade name Tarceva) is a drug used to treat non-small cell lung cancer, pancreatic cancer and several other types of cancer. It is a tyrosine kinase inhibitor, which acts on the epidermal growth factor receptor (EGFR)." - Wikipedia

NF2 Trial:

• Single-agent Erlotinib in Patients Previously Treated With Oral Etoposide in Protocol OSI-774-205 - www.ClinicalTrials.gov
• A Study Comparing Sequential Satraplatin & Erlotinib to Erlotinib in Unresectable Stage 3/4 Non-Small-Cell Lung Cancer (NSCLC) - www.ClinicalTrials.gov
• Cetuximab in Patients With Lung Adenocarcinoma Receiving Erlotinib That Have Developed "Acquired Resistance" to Erlotinib - www.ClinicalTrials.gov
• Phase 2 Study of Maintenance OSI-906 Plus Erlotinib (Tarceva), or Placebo Plus Erlotinib in Patients With Nonprogression Following 4 Cycles of Platinum-based Chemotherapy - www.ClinicalTrials.gov

Side Effects may Increase, tell your Doctor if you experience any of the following:

• Diarrhea
• Loss of Appetite
• Nausea
• Vomiting
• Heartburn
• Gas
• Constipation
• Stomach Pain
• Mouth Sores
• Weight Loss
• Extreme Tiredness
• Headache
• Bone or Muscle Pain
• Depression
• Anxiety
• Numbness, Burning, or Tingling of the Hands or Feet
• Swelling of the Arms, Hands, Feet, Ankles, or Lower Legs
• Darkening of Skin
• Hair Loss
• Change in Appearance of Hair and Nails

Serious Side Effects

• Shortness of Breath
• Cough
• Fever or Chills
• Chest Pain or Pressure
• Pain in the Arms, Neck, or Upper Back
• Rapid, Irregular, or Pounding Heartbeat
• Slow or Difficult Speech
• Dizziness or Faintness
• Weakness or Numbness of an Arm or Leg
• Unusual Bruising or Bleeding
• Black and Tarry or Bloody Stools
• Bloody Vomit or that looks like Coffee Grounds
• Dry Mouth
• Decreased Urination
• Dark Urine
• Pale or Yellow Skin
• Redness, Warmth, Pain, Tenderness, or Swelling in One Leg
• Skin Issues -
• Rash (may look like acne and may affect the skin on the face, upper chest, or back
• Blistering
• Peeling
• Dry
• Cracked Skin
• Itching
• Tenderness
• Burning
• Eye Issues -
• Dry Eyes
• Red Eyes
• Eye Pain
• Irritated Eyes
• Blurred Vision
• Sunken Eyes
• Growth of Eyelashes on the inside of the eyelid

NF2 NYC Support Group, New York
Email: Lori Davila at lori@nf2nycsupport.org
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